Biochem/physiol Actions

Cell permeable: no

Reversible: no

Product does not compete with ATP.

Primary TargetScavenges hypochlorous acid, peroxyl, superoxide, hydroxyl, and nitric oxide radicals

General description

An effective antioxidant. Scavenges hypochlorous acid, peroxyl, superoxide, hydroxyl and nitric oxide radicals. Also exhibits prooxidant properties, as demonstrated by its ability to reduce iron ions and to generate reactive sulfur-containing radicals that can damage certain proteins, such as α₁-antiproteinase and creatine kinase. DHLA has recently been shown to inhibit apoptosis in rat thymocytes induced by methylprednisolone and etoposide.

An effective antioxidant. Scavenges hypochlorous acid, peroxyl, superoxide, hydroxyl, and nitric oxide radicals. Also exhibits prooxidant properties, as demonstrated by its ability to reduce iron ions and to generate reactive sulfur-containing radicals that can damage certain proteins, such as α₁-antiproteinase and creatine kinase. DHLA has recently been shown to inhibit apoptosis in rat thymocytes induced by methylprednisolone and etoposide.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Packer, L., et al. 1997. Adv. Pharmacol. 38, 79.Bustamante, J., et al. 1995. Free Radic. Biol. Med. 19, 339.Scott, B.C., et al. 1994. Free Radic. Res. 20, 119.

Packaging

Packaged under inert gas

50 mg in Plastic ampoule

Warning

Toxicity: Irritant (B)